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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are often focused on practical aspects of the study design, such as recruitment and consent in adherence, as well as the use of standard equipment.
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A pragmatic study that involves a variety investigators and includes participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, which is vital for
프라그마틱 순위 a pragmatic trial to be reliable and to reduce bias in the results is also essential. However excessive heterogeneity could cause problems with the design of the trial.
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The purpose of pragmatic trials is to simulate real-life scenarios and gain maximum validity externally. They are usually commissioned by practitioners and policy makers to guide their decision-making. They can also be used to determine the cause-effect relationship of an intervention and
프라그마틱 슬롯 사이트 its results. However, they shouldn't be used in lieu for explanation trials.
The pragmatism concept is controversial, and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which prove the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform policy and practice decision-making. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool tried to define the traits of a pragmatic study which includes recruitment, design, implementation of the intervention and follow-up.
There is a positive increase in the number of pragmatic trials published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials that are randomized (RCTs),
프라그마틱 추천 yielded 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary care settings.
